Publications

Discover the most recent publications featuring the ultra-rapid QuickMIC® AST system.

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Browse Gradientech’s recent scientific articles and posters to learn more about the comprehensive studies behind the QuickMIC system.

The QuickMIC® system and its Gram-negative panel are CE-marked. The QuickMIC system is not FDA 510(k)-cleared and not available for clinical diagnostic use in the US.

Common phenotypic methods for antibiotic susceptibility testing (AST) of bacteria are slow, labour intensive and displays considerable technical variability. The QuickMIC system provides rapid AST using a microfluidic linear gradient.

Scientific article2024-09-26

A multicenter evaluation of a novel microfluidic rapid AST assay for Gram-negative bloodstream infections

Authors: Benjamin Berinson, Emma Davies, Jessie Torpner, Linnea Flinkfeldt, Jenny Fernberg, Amanda Åman, Johan Bergqvist, Håkan Öhrn, Jonas Ångström, Cecilia Johansson, Klara Jäder, Helena Andersson, Ehsan Ghaderi, Maria Rolf, Martin Sundqvist, Holger Rohde, Teresa Fernandez Zafra, Christer Malmberg

Published: ASM Journals: Journal of Clinical Microbiology (2024).

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Scientific article2024-09-05

Evaluation of the QuickMIC system in the rapid diagnosis of Gram-negative bacilli bacteremia

Authors: Celia García-Rivera, Andrea Ricart-Silvestre, Mónica Parra Grande, María Paz Ventero, Iryna Tyshkovska-Germak, Antonia Sánchez-Bautista, Esperanza Merino, Juan Carlos Rodríguez

Published: ASM Journals: Microbiology Spectrum (2024).

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Increasing antibiotic resistance creates challenges for the management of severe diseases such as bloodstream infection...
Poster2024-05-06

Performance of a Novel Microfluidic Rapid AST Assay for Gram-Negative Bloodstream Infections in Low and High Resistance Settings

Authors: Anna Olsson, Linnea Flinkfeldt, Emma Davies, Jessie Torpnér, Jenny Fernberg, Amanda Åman, Håkan Öhrn, Jonas Ångström, Linda Pirožkova, Valentina Kolesnikova, Julia Vahturova, Anastasia Bilozor, Celia García-Rivera, Andrea Ricart-Silvestre, Mónica Parra-Grande, Antonia Sánchez Bautista, Cecilia Johansson, Marina Ivanova, Juan Carlos Rodriguez, Christer Malmberg

Published: ESCMID Global 2024.

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Rapid antibiotic susceptibility testing (rAST) methods can significantly enhance the management of bloodstream infections. They enable clinicians to quickly select appropriate antibiotic therapy...
Poster2023-09-21

Rapid susceptibility testing of Gram-negative bloodstream infections using the QuickMIC system

Authors: Anna Olsson, Emma Davies, Jessie Torpner, Linnea Flinkfeldt, Jenny Fernberg, Amanda Åman, Håkan Öhrn, Jonas Ångström, Cecilia Johansson, Teresa Fernandez Zafra, Christer Malmberg

Published: NSCMID 2023

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Poster2023-04-06

A multicenter evaluation of a novel microfluidic rapid AST assay for Gram-negative bloodstream infections

Authors: Emma Davies, Jessie Torpner, Linnea Flinkfeldt, Jenny Fernberg, Amanda Åman, Johan Bergqvist, Håkan Öhrn, Jonas Ångström, Cecilia Johansson, Teresa Fernandez Zafra, Klara Jäder, Helena Andersson, Ehsan Ghader, Maria Rolf, Martin Sundqvist, Benjamin Berinson, Holger Rohde, Christer Malmberg

Published: 2023

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Can AST be run directly from blood without culture?🩸 We investigated this in a study with Momentum Bioscience and Uppsala University.
Poster2023-04-02

A rapid workflow for bacterial isolation and phenotypic AST directly from blood

Authors: Julia Pärssinen, Aram Kadoom, Cyrine Mestiri, Emma Davies, Amanda Åman, Jenny Fernberg, Linnea Flinkfeldt, Jessie Torpner, Johan Bergqvist, Håkan Öhrn, Jonas Ångström, Daniel Lockhart, Cecilia Johansson, William Mullen, Pernilla Lagerbäck, Thomas Tängdén & Christer Malmberg

Published: ECCMID 2023

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Sepsis är den vanligaste dödsorsaken i världen med antalet fall per år uppskattat till 48,9 miljoner...
In SwedishPoster2022-05-06

Utvärdering av snabb-AST systemet QuickMIC® med kliniska blodkulturer

Authors: Christer Malmberg, Jessie Torpner, Jenny Fernberg, Håkan Öhrn, Cecilia Johansson, Thomas Tängdén & Johan Kreuger

Published: 2022

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Carbapenem-resistant and 3rd generation cephalosporin resistant Enterobacterales have emerged as serious threats to global health in the last decade.
Poster2022-04-23

Rapid detection of carbapenem and third-generation cephalosporin resistance from positive blood cultures

Authors: Christer Malmberg, Jessie Torpnér, Linnea Flinkfeldt, Amanda Åman, Håkan Öhrn, Jonas Ångström, Cecilia Johansson, Thomas Tängdén

Published: ECCMID 2022

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Resistant blood stream infections are on the rise, hence there is an urgent need for faster AST diagnostics to guide treatment and reduce antibiotic misuse...

Poster2022-04-08

Clinical evaluation of the QuickMIC AST system for ultra-rapid MIC determination using positive blodcultures from patients with bacteraemia

Authors: Helena E. Andersson, Klara Jäder, Ehsan Ghaderi, Johan Lind

Published: ECCMID 2022

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Antimicrobial resistance challenges empirical antibiotic therapy for severely ill patients, emphasising the need for rapid susceptibility diagnostics...
Scientific article2022-03-23

Evaluation of the Speed, Accuracy and Precision of the QuickMIC Rapid Antibiotic Susceptibility Testing Assay With Gram-Negative Bacteria in a Clinical Setting

Authors: Christer Malmberg, Jessie Torpner, Jenny Fernberg, Håkan Öhrn, Jonas Ångström, Cecilia Johansson, Thomas Tängdén, Johan Kreuger

Published: Frontiers in Cellular and Infection Microbiology (2022)

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Poster2021-07-09

Evaluation of the QuickMIC rapid AST assay for blood cultures in a clinical setting

Authors: Christer Malmberg, Jessie Torpner, Jenny Fernberg, Håkan Öhrn, Cecilia Johansson, Thomas Tängdén, Johan Kreuger

Published: ECCMID 2021

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Many patients with severe infections receive inappropriate empirical treatment, and rapid detection of bacterial antibiotic susceptibility can improve clinical outcome and reduce mortality.
Scientific article2020-02-20

A multiplex fluidic chip for rapid phenotypic AST

Authors: Pikkei Wistrand-Yuen, Christer Malmberg, Nikos Fatsis-Kavalopoulos, Moritz Lübke, Thomas Tängdén, Johan Kreuger

Published: 2020

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